BARC/PUB/2004/0462

 
 

Enantiomeric synthesis of the SPIKET-P enantiomers

 
     
 
Author(s)

Sharma, A.; Iyer, P.; Gamre, S.; Chattopadhyay, S.
(BOD)

Source

Synthesis, 2004. Vol. 7: pp. 1037-1040

ABSTRACT

A convenient synthesis of the antipodes of the title com-pound has been developed starting from (R)-1,2,5,6-dicyclohexy-lidene mannitol. Some of the key features of the syntheses were simple reaction protocols, and stereoselective inversion of chiral1,2-diol moiety via neighbouring group assisted acetylation.

 
 
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