Cross sections for (γ, n) reaction at bremsstrahlung end point energies of 10 and 12.5MeV on niobium have been measured by the activation technique. Induced activities were measured by a high-resolution γ-ray spectrometer with a high-purity germanium (HPGe) detector. Theoretically the (γ, n) cross-section of ⁹³Nb as a function of photon energies were also calculated using TALYS 1.4 computer code. We compared the measured data with the flux weighted average values from the available literature data based on experiments with mono-energetic photons and the theoretical calculation by the model code TALYS 1.4. The experimental values are found to be in good agreement with the theoretical value from TALYS 1.4 but are slightly higher than the flux-weighted values from mono-energetic photons.