The enzymatic degradation of textile dyes offers an alternative approach over the conventional waste water treatment processes. Covalent immobilization of the enzymes onto insoluble supports not only permits their reusability and easy  separation of enzymes from the product but also, if properly performed, may improve their activities, stability and hence reduces the cost of process. In the present work, epoxy functionalized polyethersulfone (PES) was synthesized via radiation induced polymerization of poly(2,3-epoxypropyl methacrylate) [poly(EPMA)] in PES-NMP (N-methyl-2-pyrrolidone) solution using ⁶⁰Co-gamma radiation source. Poly(EPMA)-functionalized-PES [poly(EPMA)-f-PES] beads were fabricated via phase inversion route using water as the anti solvent. Laccase was covalently immobilized on to the beads via one step-room temperature coupling reaction of amine group of enzyme with the epoxy group of poly(EPMA). Enzyme activity was assayed using 2,2'-azino-bis(3-ethylthiazoline-6-sulfonate) (ABTS) as the substrate. Effect of temperature and pH on the free and immobilized enzyme activity was studied. The immobilized laccase was successfully employed to degrade Acid Red 1 (AR1) dye in aqueous solution. Room temperature incubation of the laccase immobilized poly(EPMA)-f-PES beads with AR1 dye (~10 ppm) resulted in ~88% degradation of the dye over a period of 15 days.