BARC/PUB/2005/0584
(R)-2,3-Cyclohexylideneglyceraldehyde, a novel template for facile and simple entry into chiral hydroxy γ-lactones: synthesis of (-)-muricatacin
Dhotare, B.; Chattopadhyay, A. (BOD)
Tetrahedron Letters, 2005. Vol. 46: pp. 3103-3105
(R)-2,3-Cyclohexylideneglyceraldehyde1 has been used in a simple and efficient synthesis of (-)-muricatacin 10. The required chiron, syn-alkanetriol 2a was prepared by the reduction of a ketone 3 derived from 1.