The role of thermal activation in the pre-dose sensitization of the 110 °C TL glow peak of quartz has been hypothesized to transfer holes from reservoir centre, R, to luminescence centre, L. But, the thermal treatment has been reported to sensitize this peak, also, in an independent mode. So, a comparative analysis of the impact of thermal and pre-dose treatment on the TL properties of the 110 °C signal, observed by various workers, has been undertaken in this paper. Also experiments were carried out to observe thermal sensitization component at the temperatures which are used in the pre-dose sensitization measurements. The study seems to support the existence of an inherent pure thermal sensitization component in the pre-dose sensitization mechanism.