Dye-sensitized solar cells (DSSCs) are fabricated based on rutile TiO₂ microspheres that are synthesized by a hydrothermal route. We found that, with increasing deposition time, semi microspheres get converted into microspheres. Our results show that the TiO₂ -based cells exhibit a noticeable improvement in the overall efficiency: maximum 3.81% versus 0.67% for the reference cell made of a rutile TiO₂ semispherical nanocrystalline film. This extraordinary result is attributed to the effective light trapping and dye loading resulting in the highest efficiency 3.81%.