Natural biological fluid Cows(Bosindicus) urine precipitates out the toxic heavy metal ions when added to450ppm-21660ppm ranges in the solution of toxic heavy metals like Cadmium, Lead and Mercury. The dried residue was tested by Energy Dispersion X Ray Fluorescence for presence of these metals and found positive. The filtrate solution were analyzed the ICP-AES results show that there is almost 3000 times decrease for cadmium and for Lead and Mercury it is 320 times decrease for Lead and 360 times for Mercury , the dilution factor has been taken account for the results.. The filtrate solution were also analyzed by GC-MS and compared to GC-MS chromatogram of cow’s urine to find the ingredients responsible for precipitations. However, it seems alkaline pH of cow’s urine is one of the causes responsible for the precipitations apart from synergistic effects of so many ingredients of cows urine. The use of natural biological fluid like cows urine heralds a new precipitating agent which is biodegradable and highly environmental friendly. The results of this experiment will have far reaching impact in metal processing industry of these heavy metals , detoxification of heavy metals ions in the solution in bulk quantities since cows urine are available in plenty.