Auranyl Schiff base complex [UO₂{OC₆H₄N=C(H)C₆H₄O}^.H₂O] has been immobilized inside the periodic mesopore channels of MCM-41 by the impregnation route. The samples have been characterized by XRD, N₂ adsorption/desorption, TG-DTA, DR UV vis, ²⁹Si MAS NMR and FTIR techniques. While the host is found to retain its structural integrity, the surface area and the pore volume decrease considerably as a result of the intrapore confinement of complex molecules. The spectroscopy results indicate that the complex molecules are anchored with the silanol groups of MCM-41 via hydrogen bonding.