This study is focused on the scale-up of solvent extraction in microbore tubes. A mono block distributor with integrated microfluidic junctions (MDIMJ) is used for generating liquid –liquid dispersion and feeding the parallel microbore tubes. Experiments involve solvent extraction of U (VI) from simulated lean streams using 30% (v/v) tributyl phosphate (TBP) in dodecane. Polytetrafluoroethylene (PTFE) microbore tubes are used as a microscale contactor. The effects of inlet flow rate and O/A ratio on stage efficiency and percentage extraction (PE) are studied. Maximum capacity tested is 1.33 × 10 ^–6m³/s (4.8LPH). With O/A = 2/1, more than 90% extraction is achieved in a contact time of less than 3 s.