Catechol (1, 2 dihydroxybenzene) is an industrial feedstock and acts as one of the environmental pollutants causing various health issues like skin irritation, eye damage etc. It is a challenge to the researchers to design efficient sensing material for catechol. Employing the advanced Density Functional Theory (DFT) simulation, we have probed the catechol sensing capabilities of pristine and metal-decorated 2D dichalcogenide MoS₂. We have presented the charge transfer as well as bonding means of catechol on pure and metal-decorated MoS₂ through Bader charge analysis and orbital interaction. DFT results predict Ti-decorated MoS₂ to be a promising catechol sensing material due to higher binding energy of catechol on that. It is found that more charge transport from O 2p orbital of catechol to metal d orbital and shorter O-Ti bond length, stronger bonding through p-d hybridization happens for Ti-decorated MoS₂. The stability of the structure has been inspected through ab-initio Molecular Dynamics calculations at 300 K and the structure was found to be stable. Based on the presented conjectural predictions, we put forward Ti-decorated MoS₂ being a possible nanomaterial for catechol-detection.