Single- and multi-nucleon transfer reactions, namely, ²⁰⁶Pb(¹⁸O,²⁰O),²⁰⁶Pb(¹⁸O,¹⁹O),²⁰⁶Pb(¹⁸O,¹⁷O),²⁰⁶Pb(¹⁸O,¹⁶O),²⁰⁶Pb(¹⁸O,¹⁸N),²⁰⁶Pb(¹⁸O,¹⁷N),²⁰⁶Pb(¹⁸O,¹⁶N),²⁰⁶Pb(¹⁸O,¹⁵N),²⁰⁶Pb(¹⁸O,¹⁴N),²⁰⁶Pb(¹⁸O,¹⁶C),²⁰⁶Pb(¹⁸O,¹⁵C),²⁰⁶Pb(¹⁸O,¹⁴C),²⁰⁶Pb(¹⁸O,¹³C),²⁰⁶Pb(¹⁸O,¹²C),²⁰⁶Pb(¹⁸O,¹²B),²⁰⁶Pb(¹⁸O,¹¹B),²⁰⁶Pb(¹⁸O,¹⁰B),²⁰⁶Pb(¹⁸O,¹⁰Be), and ²⁰⁶Pb(¹⁸O,⁹Be), have been studied at an incident ¹⁸O energy of 139 MeV. The total kinetic energy loss (TKEL) spectrum and angular distribution of reaction products have been measured. The Q value and angle integrated cross sections are deduced. Angular distributions for the elastically scattered ¹⁸O particles are also measured. Fully microscopic time-dependent Hartree-Fock (TDHF) calculations, based on the independent single-nucleon transfer mode, have been carried out and are compared with experimental data of multinucleon transfer reactions. The TDHF calculations provide reasonable agreement with the experimental data for cases where one- and two-nucleon transfer is involved; the discrepancy is large for multinucleon transfer reactions. The effect of particle evaporation on the production cross sections has been studied. Inclusion of particle evaporation effects, though improving the results, could not reproduce the measured cross sections. Possible origins of these discrepancies are discussed.