The laser photolysis-laser-induced fluorescence method was used for measuring the kinetic parameters of the reaction of OH radicals with CF₃CH₂OCH₂CF₃ (2,2,2-trifluoroethyl ether), in the temperature range of 298-365 K. The bimolecular rate coefficient at 298 K, k_II(298), was measured to be (1.47 ± 0.03) X 10^-13 cm³ molecule^-1 s^-1, and the temperature dependence of k_II was determined to be (4.5±0.8)—10^-12 exp[-(1030 ± 60)/T] cm³ molecule^-1 s^-1. The error quoted is 1s of the linear regression of the respective plots. The rate coefficient at room temperature is very close to the average of the three previous measurements, whereas the values of E_a/R and the A-factor are higher than the two previously reported values.