While the ⁹⁰Sr/⁹⁰Y generator is the exclusive source of obtaining ‘no carrier added’ ⁹⁰Y for targeted therapy, the presence of trace metals in the radio labeling solutions poses a serious challenge owing to their ability to diminish the ⁹⁰Y complexation yields with bifunctional chelators (BFCs). p-SCN-Bn-P CTAis a novel ligand having faster complexation kinetics with a number of radiometals. In this work, a systematic investigation was performed to evaluate the chelating ability of p-SCN-Bn-PCTA for ⁹⁰Y and the influence of trace metal ions on it’s complexation with ⁹⁰Y incomparison top-SCN-Bn-DTPAandp-SCN-Bn-DOTA using ⁹⁰YCl₃ obtained from an electrochemical generator. Results from our study indicate that while p-SCN-Bn-PCTA gave very good radiolabeling yields with ⁹⁰Y when the reaction was carried out by heating for few minutes, it was most sensitive to the presence of trace metals, especially Fe(III). An independent and useful observation is that p-SCN-Bn-PCTA could be considered as the ligand of choice for assessing the chemical purity of generator derived ⁹⁰Y.