Uranium is an essential element in nuclear industry with the largest amount present in sea water. Also it is one of the most toxic heavy metals present on earth. Considering this, many adsorbents have been developed for uranium extraction with each having its merits and demerits. This review discusses the application of magnetic nanoparticles (MNPs) as sorbent for uranium, challenges associated and the present status. A glimpse about the difficulties associated with uranium extraction from sea water will also be discussed. The review also focuses on the gaps needs to be filled and the future perspective of these materials for the said purpose.