Electromagnetic transition rates provide an important test for nuclear structure models. The nucleus 8Be exhibits a pronounced alpha-cluster structure and is a building block for more complex cluster nuclei. Here we report on the first observation of the gamma transition between the 4+and 2+ states of 8Be in the 4He+4He reaction. The measured on-resonance cross section of 165 ±54 nb leads to a B(E2) of 25±8 e2fm4, in good agreement with alpha-cluster models and sophisticated ab initio structure calculations