Recovery of uranium from the raffinate stream of uranium extraction plant (UNRS) has been investigated with TBP/dodecane–NaHCO₃ system using hollow fiber dispersion liquid membrane with the objective of polishing of streams and recycle/safe disposal of effluent water. A mathematical model has been developed to predict the transport of uranium  through Dispersed Liquid Membrane (DLM) configuration in hollow fiber contactor. The model predicts the rate of change of concentration in the aqueous feed phase fl owing through the lumens in recirculating mode. It takes into account concentration change during fl ow along the lumen, complexation reaction at the aqueous–organic interface at the pore-entrance of lumen and diffusive transport through aqueous and organic films. The equilibrium distribution data for U(VI) for various extractant concentrations and various strippants have been generated, with independent experiments using real raffinate stream. Also, the mass-transfer resistances at the aqueous and organic films have been estimated independently. These data have been used in the model for prediction of uranium transport. The predictions of the model have been substantiated with experimental results and found to be in good agreement. Parametric studies have been carried out with the present system to obtain the best operating conditions for efficient separation. Besides showing good stability, the DLM configuration gives complete recovery of uranium from pure uranyl nitrate solution as well as nitrate based raffinate of uranium extraction plant. The present work provides valuable input for design and scale up of the process in view of commercial application.