Polymer inclusion membranes (PIM) containing TODGA (N,N,N′N′-tetra-n-octyl diglycolamide) wereevaluated for the separation of actinide ions such as Am³⁺, Pu⁴⁺, UO₂²⁺and Th⁴⁺from acidic feeds. ThePIMs were prepared using cellulose triacetate (CTA) as the polymer matrix and 2-nitrophenyloctyl ether(NPOE) as the plasticizer along with the diglycolamide carrier extractants and were characterized by con-ventional techniques such as XRD, thermal analysis and AFM. The PIM composition was optimized by aseries of studies which involved variation in the CTA, NPOE and carrier concentration which suggested 58%TODGA, 30% NPOE and 12% CTA to be optimum. The uptake studies were carried out using feed solutionscontaining varying concentrations of nitric acid and showed the trend: Am³⁺> Pu⁴⁺> Th⁴⁺> UO₂²⁺.Transport studies were carried out in a two-compartment cell where nitric acid concentration the feedwas varied (1–3 M) while the receiver compartment contained alpha-hydroxy-iso-butyric acid (AHIBA).The actinide ion transport efficiencies with TODGA containing PIMs followed the same trend as seenin the uptake studies. The AFM patterns of the PIMs changed when loaded with Eu³⁺carrier (used as asurrogate for Am³⁺) while the regenerated membranes have displayed comparable morphologies. Diffu-sion coefficient values were experimentally obtained from the transport studies and were found to be8.89 × 10⁻⁸cm²/s for Am³⁺transport.