Zr-2.5Nb alloy tubes in cold worked and stress relieved (CWSR) condition serve as pressure boundary for hot coolant in Indian Pressurized Heavy Water Reactor (IPHWR). Due to both microstructural and crystallographic anisotropy, the mechanical properties in general and fracture behavior in particular are anisotropic for this material/component. In this work impact behavior of the pressure tube material was characterized over a range of temperature by impact test using specimens with crack growth direction along axial and transverse directions of the tubes. It has been found that both temperature and orientation have strong influence on the absorbed impact energy.