A hydrochemical study was undertaken in ura-nium impacted districts of southwest Punjab for evaluating the spatial and vertical trends as well as correlations with other hydrochemical parameters. Results infer that U is present in all samples (12.2–621μgl^-1) and 90% are contaminated. Contour diagram depicts contamination in entire region excepting some pockets in central part of the study area. Shallow zones (<50 m bgl) show higher U compared to deeper ones. Hydrochemistry infers a com-mon source of U for both shallow and deep zones and alkalinity as the governing factor for U mobilization from the sediments.