An environment friendly approach towards heavy metal remediation from water is the need of the hour. A novel approach to heavy metal bioremediation from water was attempted using axenic cultures of the photoautotrophic cyanobacterium, Nostoc muscorum immobilised on to glass surface through the formation of biofilms. Being a biofilm, it exhibited much higher cellular integrity than cell suspension cultures when exposed to high concentrations of cadmium, and could also withstand the harsh conditions prevalent in industrial effluents. Being a photosynthetic organism, culturing of N. muscorum as a biofilm was achieved with minimal requirements, such as water with minerals, light and stationary conditions, which also enabled ease of scalability. The strong adherence of the N. muscorum biofilm to the glass surface was beneficial as (i) no diffusion of cell mass on to the media was observed even with the use of top-end stirrer, (ii) no expensive separation techniques were required for separation of biomass from the treated solution, and (iii) direct contact of the solution containing metals to the active components on biofilm surface allowed better interaction. The N. muscorum biofilm exhibited the capability to sequester Cd(II) in the pH range 5-9, concentration range < 0.05 ppm to 100 ppm and from different waste waters. Sequestration of Cd(II) resulted in cell surface changes, the mode of sequestration being chemisorption through the > C=O and > C=N functional groups, and followed the Langmuir's adsorption isotherm. It is proposed to use the N. muscorum biofilm as a potential green technology for waste water treatment in future.